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. 2018 Jan 4;13(1):e0190509. doi: 10.1371/journal.pone.0190509

Table 2. In-vitro antioxidant activity of drugs showing good anti-glycation activity.

Drug DPPH Radical scavenging activity Fe+2 Chelation activity
% Inhibition IC50 ± SEM1 (μM) % Inhibition IC50 ± SEM1 (μM)
Nimesulide (3) -17.13 NA2 -7.4 NA2
Phloroglucinol dihydrate (11) -2.5 NA2 -2.2 NA2
Gallic acid3 93.11 23.34 ± 0.43
EDTA - - 99.99 131.00 ± 0.01

1IC50 value is presented in μM and as mean ± standard error of mean;

2NA: Not active;

3, Standard inhibitors for antioxidant studies