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. Author manuscript; available in PMC: 2018 Dec 18.
Published in final edited form as: Vaccine. 2017 Nov 14;35(51):7121–7126. doi: 10.1016/j.vaccine.2017.10.081

Fig. 3.

Fig. 3

The evaluation of cross-boosting effect. Balb/c mice (n=10) were first immunized with Vi vaccine (Vi) or GelSite-OAc™ (G) followed by the same or a different vaccine for the 2nd and third immunization. Mice were immunized three times and four weeks apart. Specific IgG antibodies were measured with Vi polysaccharide (A) or GelSite-OAc™(B). G, GelSite-OAc™; Vi, Vi vaccine. The asterisks indicate significant difference (p<0.05) as compared to the antibody concentration at week 2 after the first immunization.