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UGT1A1 gene polymorphisms and toxicities (≥grade 3)
| −/− | *6/− | *7/− | *27/− | *28/− | |
|---|---|---|---|---|---|
| Febrile neutropenia | 0 | 1 | 0 | 1 | 0 |
| (%) | (0) | (10) | (0) | (50) | (0) |
| Leukopenia | 1 | 5 | 0 | 1 | 3 |
| (%) | (10) | (50) | (0) | (50) | (43) |
| Neutropenia | 2 | 5 | 0 | 1 | 3 |
| (%) | (20) | (50) | (0) | (50) | (43) |
| Anemia | 2 | 2 | 0 | 0 | 0 |
| (%) | (20) | (20) | (0) | (0) | (0) |
| Thrombocytopenia | 0 | 0 | 0 | 0 | 1 |
| (%) | (0) | (0) | (0) | (0) | (14) |
| Diarrhea | 0 | 3 | 0 | 0 | 0 |
| (%) | (0) | (30) | (0) | (0) | (0) |
| Pneumonitis | 0 | 0 | 1 | 0 | 1† |
| (%) | (0) | (0) | (50) | (0) | (14) |
Grade 5.
