Table 3.
Prognostic factors associated with overall survival in univariate and multivariate analysis
| All cases | Adjuvant chemotherapy cases | |||||||
|---|---|---|---|---|---|---|---|---|
| Factors | Univariate | Multivariate | HR | 95% CI | Univariate | Multivariate | HR | 95% CI |
| Age | ||||||||
| >70/≤70 | < 0.01 | < 0.01 | 2.5 | 1.6–4.0 | 0.06 | — | — | — |
| Gender | ||||||||
| Male/female | < 0.01 | < 0.01 | 3.0 | 1.4–6.8 | 0.41 | — | — | — |
| Smoking index | ||||||||
| ≥ 400/< 400 | < 0.01 | 0.77 | — | — | 0.65 | — | — | — |
| ECOG PS | ||||||||
| ≥2/0–1 | < 0.01 | 0.01 | 11 | 1.8–52 | — | — | — | — |
| H‐J classification | ||||||||
| ≥3/1–2 | 0.02 | 0.42 | — | — | 0.73 | — | — | — |
| PLR | ||||||||
| >162/≤162 | < 0.01 | < 0.01 | 1.9 | 1.2–3.2 | < 0.01 | 0.03 | 2.3 | 1.1–4.6 |
| Clinical stage | ||||||||
| ≥ II/I | < 0.01 | 0.03 | 1.8 | 1.1–3.0 | 0.01 | 0.09 | — | — |
| Pathological stage | ||||||||
| ≥ II/I | < 0.01 | < 0.01 | 2.5 | 1.5–4.2 | — | — | — | — |
| Histology | ||||||||
| Non‐ad/ad | < 0.01 | < 0.01 | 2.0 | 1.2–3.6 | 0.08 | — | — | — |
| Postoperative complications | ||||||||
| With/without | 0.05 | — | — | — | 0.07 | — | — | — |
Ad, adenocarcinoma; CI, confidence interval; ECOG PS, Eastern Cooperative Oncology Group performance status; H‐J, Hugh‐Jones; HR, hazard ratio; PLR, platelet‐to‐lymphocyte ratio.