Table 4.

Correlation analysis of oHSV1‐hTERT‐GFP and CellSearch CTC detection methods

Type	Stage	Total number of patients	oHSV1‐hTERT‐GFP		CellSearch		P
			Number of patients with ≥ 4 CTCs/4 mL blood	Sensitivity	Number of patients with ≥ 1 CTC	Sensitivity
Adenocarcinoma	I–III	11	8	0.727	3	0.273	0.063
	IV	34	23	0.676	14	0.412	0.004
	Total	45	31	0.689	17	0.378	0.000
Squamous cell carcinoma	I–III	6	4	0.667	1	0.167	0.250
	IV	4	2	0.500	0	0	NA
	Total	10	6	0.600	1	0.100	0.063
Small cell lung cancer	LD	6	5	0.833	2	0.333	0.250
	ED	5	5	1.000	2	0.400	NA
	Total	11	10	0.909	4	0.364	0.031

CTC, circulating tumor cells; ED, extensive disease; LD, limited disease; NA, not available.