Table 4. Antibiotic therapy for pyomyositis.

Disease classification	Antibiotic	Adult dose
Empirical therapy	Ampicillin/sulbactam or	3 g q6 h IV
	cefepime or	2 g q8 h IV
	piperacillin/tazobactam or	3.375–4.5 g q6–8 h IV
	ertapenem	1 g q24 h IV
Streptococcus	Penicillin	2–4 million units q4–6 h IV
	Plus
	clindamycin	600–900 mg q8 h IV
Methicillin-susceptible S. aureus	Nafcillin or	1–2 g q4 h IV
	cefazolin	1–2 g q8 h IV
Methicillin-resistance S. aureus	Vancomycin or	15 mg/kg q12 h IV
	teicoplanin or	6–12 mg/kg q24 h IV
	linezolid	600 mg q12 h IV

IV, intravenous; PO, per os.