Table 2.

Recommended antifungal prophylaxis in patients with neutropenia (< 500 cells/μL > 7 days)

Intention	Intervention	SoR	QoE
Prevent IFI in patients with neutropenia (< 500 cells/μL > 7 days), excluding alloSCTa	Posaconazole	A	Ib
		B	IIIc
	Amphotericin B, liposomal, inhalation	B	IId
	Amphotericin B, liposomal, iv	C	I
	Caspofungin	C	I
	Fluconazole	C	I
	Itraconazole	C	I
	Itraconazole, iv	C	I
	Voriconazole	C	II
	Amphotericin B deoxycholate	D	I
	Micafungin	C	IIh
	Isavuconazole	C	IIu

^aCurrently, no recommendations for ALL patients applicable

^bStrong recommendation in AML/MDS remission induction chemotherapy only

^cOther settings, e.g. very severe aplastic anaemia and palliative treatment of MDS

^dAll patients received fluconazole—dose and route were not reported