Table 1. Number of persons included in iPSYCHs population-based sample of the Danish population born 1981–2005.
Number of persons |
|||||
---|---|---|---|---|---|
Group membershipa | ICD10 diagnosesb | Follow-up period | Initial Sample | Blood spots available in Biobank and sent to Broad | Passed Sample QC |
Schizophreniac | F20 | 2009–2012 | 3540 | 2830 | 2738 |
Bipolar disorder | F30–F31 | 1994–2012 | 1928 | 1488 | 1452 |
Affective disorder | F30–F39 | 1994–2012 | 26 380 | 23 532 | 22 809 |
Autism | F84.0, F84.1, F84.5, F84.8 or F84.9 | 1994–2012 | 16 146 | 15 418 | 14 812 |
ADHD | F90.0 | 1994–2012 | 18 726 | 17 835 | 17 249 |
Any case | All ICD codes listed above | 57 377 | 52 867 | 51 101 | |
Population-based cohort | Random sampling, i.e., disregarding any diagnostic information | 30 000 | 28 650 | 27 605 | |
Total number of persons | 86 189 | 80 422 | 77 639 |
Abbreviations: ADHD, attention-deficit/hyperactivity disorder; ICD-10, International Classification of Diseases, 10th revision; iPSYCH, Integrative Psychiatric Research; QC, quality control.
Groups are not mutually exclusive.
Initial ICD10 diagnosis used to select case groups. Identification was performed through linkage to the Danish Psychiatric Central Research Register. At the time of linkage, the register contained all contacts up until 31/12/2012.
Include all persons first diagnosed with schizophrenia during the period from 1 January 2009 to 31 December 2012 and persons first diagnosed with schizophrenia before 1 January 2009 that were not already genotyped (N=923). A total of 1887 persons first diagnosed with schizophrenia before 1 January 2009 were previously genotyped (see Supplementary Text 1).