Table 4.
Results of liner univariate analysis and linear multivariate analysis with mean amplitude of glycemic excursions as the dependent variable
| Variables | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| β | 95% CI | P‐value | β | 95% CI | P‐value | |
| Intercept | 38.7 | 20.2, 57.1 | <0.01 | |||
| HbA1c | 1.5 | –0.41, 3.4 | 0.12 | |||
| FPG | 0.06 | –0.01, 0.13 | 0.10 | |||
| Mean glucose level | 0.14 | 0.08, 0.21 | <0.01 | 0.07 | 0.01, 0.12 | 0.01 |
| SD | 1.4 | 1.2, 1.5 | <0.01 | 1.6 | 1.3, 1.8 | <0.01 |
| Maximum glucose levels | 0.21 | 0.17, 0.25 | <0.01 | 0.16 | 0.08, 0.24 | <0.01 |
| Minimum glucose levels | 0.02 | –0.07, 0.10 | 0.69 | 0.25 | 0.14, 0.37 | <0.01 |
| AUC >180 mg/dL | 0.21 | 0.11, 0.32 | <0.01 | –0.14 | –0.32, 0.05 | 0.16 |
| Percentage of AUC >180 mg/dL | 0.29 | 0.19, 0.39 | <0.01 | |||
| AOC <70 mg/dL | –9.0 | –27.6, 9.6 | 0.34 | –11.0 | –23.3, 1.1 | 0.07 |
| Percentage of AOC <70 mg/dL | 0.80 | –3.5, 5.1 | 0.72 | |||
| Pre‐meal glucose level (breakfast) | 0.05 | –0.03, 0.13 | 0.20 | |||
| Pre‐meal glucose level (lunch) | 0.09 | 0.03, 0.14 | <0.01 | |||
| Pre‐meal glucose level (dinner) | 0.04 | –0.03, 0.11 | 0.21 | –0.11 | –0.19, –0.04 | <0.01 |
| Postprandial peak glucose (breakfast) | 0.19 | 0.14, 0.24 | <0.01 | 0.07 | 0.02, 0.12 | 0.01 |
| Postprandial peak glucose (lunch) | 0.13 | 0.09, 0.18 | <0.01 | |||
| Postprandial peak glucose (dinner) | 0.16 | 0.11, 0.21 | <0.01 | |||
Multivariate stepwise regression analysis with mean amplitude of glycemic excursions as the dependent variable, and age, sex, body mass index, glycated hemoglobin, fasting plasma glucose (FPG), mean glucose level, standard deviation (SD), maximum glucose levels, minimum glucose levels, area under the blood concentration–time curve (AUC) >180 mg/dL, percentage of AUC >180 mg/dL, area over the blood concentration–time curve (AOC) <70 mg/dL, percentage of AOC <70 mg/dL, pre‐meal glucose level (breakfast), pre‐meal glucose level (lunch), pre‐meal glucose level (dinner), postprandial peak glucose (breakfast), postprandial peak glucose (lunch), postprandial peak glucose (dinner) as the independent variables. All variables were measured by the continuous glucose monitoring system.