Table II.
Comparison of S-IPI, R-IPI to NCCN-IPI for risk stratification and outcomes of 2-year PFS and OS in these risk groups redistributed by interim PET/CT into PET negative (−) and positive (+) groups.
| S-IPI | R-IPI | NCCN-IPI | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Variable | Low risk (0–2) | High risk (3–5) | Very good (0) | Good (1–2) | Poor (3–5) | Low risk (0–3) | High risk (4–8) | |||||||
| 2-year | 74 (64–81) | 37 (26–48) | 97 (80–100) | 63 (51–73) | 37 (25–48) | 70 (61–77) | 37 (24–49) | |||||||
| PFS | PET(−) | PET(+) | PET(−) | PET(+) | PET(−) | PET(+) | PET(−) | PET(+) | PET(−) | PET(+) | PET(−) | PET(+) | PET(−) | PET(+) |
| 88 (78–94) | 31 (15–49) | 66 (44–80) | 18 (8–31) | 100 | 97 (80–100) | 82 (67–92) | 26 (11–44) | 66 (44–81) | 18 (8–31) | 85 (76–91) | 22 (10–38) | 65 (41–82) | 20 (9–34) | |
| 2-year | 90 (82–94) | 66 (53–76) | 97 (80–100) | 85 (75–91) | 60 (47–71) | 88 (80–93) | 65 (51–76) | |||||||
| OS | PET(−) | PET(+) | PET(−) | PET(+) | PET(−) | PET(+) | PET(−) | PET(+) | PET(−) | PET(+) | PET(−) | PET(+) | PET(−) | PET(+) |
| 98 (90–99) | 65 (43–80) | 82 (59–93) | 45 (29–60) | 100 | 97 (80–100) | 94 (82–98) | 63 (40–79) | 92 (71–98) | 48 (32–63) | 95 (88–98) | 60 (41–74) | 89 (63–97) | 51 (33–66) | |
All results are presented as the % (95% CI). OS, overall survival; PFS, progression free survival; S-IPI, standard International Prognostic Index; R-IPI, revised International Prognostic Index; NCCN-IPI, enhanced International Prognostic Index; PET, positron emission tomography; CT, computed tomography.