Table 4.
Ethnicity-stratified logistic estimates of high-risk adenomatous polyps according to total, soluble and insoluble dietary fibre quartiles (n=2194)
| Polyps | Ethnicity | pinteraction | |||||
| White (n=1920) | Non-white (n=274) | ||||||
| Controls | Cases | Adjusted* OR (95% CI) |
Controls | Cases | Adjusted* OR (95% CI) |
||
| Total fibre† | |||||||
| Q1 | 272 | 194 | 1.0 (ref.) | 48 | 34 | 1.0 (ref.) | 0.03 |
| Q2 | 293 | 193 | 0.92 (0.70 to1.22) | 37 | 22 | 0.67 (0.31 to1.44) | |
| Q3 | 286 | 199 | 0.97 (0.72 to1.31) | 48 | 16 | 0.35 (0.15 to0.80) | |
| Q4 | 297 | 186 | 0.88 (0.61 to1.25) | 50 | 19 | 0.33 (0.12 to0.89) | |
| Ptrend=0.57 | Ptrend=0.01 | ||||||
| Soluble fibre‡ | |||||||
| Q1 | 269 | 199 | 1.0 (ref.) | 45 | 34 | 1.0 (ref.) | 0.05 |
| Q2 | 301 | 190 | 0.82 (0.62 to1.08) | 40 | 20 | 0.45 (0.20 to0.97) | |
| Q3 | 273 | 203 | 0.91 (0.68 to1.23) | 48 | 21 | 0.40 (0.18 to0.90) | |
| Q4 | 305 | 180 | 0.70 (0.48 to1.01) | 50 | 16 | 0.25 (0.09 to0.71) | |
| Ptrend=0.13 | Ptrend=0.01 | ||||||
| Insoluble fibre§ | |||||||
| Q1 | 271 | 194 | 1.0 (ref.) | 49 | 33 | 1.0 (ref.) | 0.01 |
| Q2 | 293 | 187 | 0.91 (0.69 to1.21) | 40 | 25 | 0.78 (0.37 to1.63) | |
| Q3 | 284 | 204 | 1.05 (0.78 to1.41) | 43 | 17 | 0.41 (0.17 to0.94) | |
| Q4 | 300 | 187 | 0.88 (0.62 to1.25) | 51 | 16 | 0.28 (0.11 to0.76) | |
| Ptrend=0.73 | Ptrend<0.01 | ||||||
*Multivariate models adjusted for age, sex, BMI, total daily caloric intake, smoking status (never, former and current), reason for colonoscopy (average risk, FOBT/FIT+ and family history) and family history of polyps (yes versus no).
†Quartile cut-offs for total dietary fibre intake were: ≤14.3, 14.31–19.14, 19.15–25.51 and ≥25.52 g/day.
‡Quartile cut-offs for dietary soluble fibre intake were: ≤4.83, 4.84–6.42, 6.43–8.44 and ≥8.45 g/day.
§Quartile cut-offs for dietary insoluble fibre intake were: ≤9.36, 9.37–12.72, 12.73–16.96 and ≥16.98 g/day.
Ref., reference group.