Table III.
Clinicopathological association of HNF-4α in human GC tissues.
| HNF-4α expression | |||||
|---|---|---|---|---|---|
| Characteristics | – | + | ++ | +++ | P-value |
| n | 2 | 15 | 48 | 61 | |
| Age (years) | 0.682 | ||||
| <56 | 0 | 8 | 23 | 32 | |
| ≥56 | 2 | 7 | 25 | 29 | |
| Gender | 0.563 | ||||
| Male | 1 | 6 | 26 | 27 | |
| Female | 1 | 9 | 22 | 34 | |
| Differentiation | 0.499 | ||||
| Well | 1 | 5 | 15 | 18 | |
| Moderate | 1 | 3 | 20 | 21 | |
| Poor | 0 | 7 | 13 | 22 | |
| Tumor stage | 0.015 | ||||
| T1 | 0 | 6 | 8 | 7 | |
| T2 | 1 | 4 | 13 | 14 | |
| T3 | 1 | 2 | 15 | 18 | |
| T4 | 0 | 3 | 12 | 22 | |
| Lymph node metastasis | 0.007 | ||||
| N0 | 0 | 4 | 10 | 6 | |
| N1 | 1 | 5 | 12 | 9 | |
| N2 | 0 | 3 | 12 | 20 | |
| N3 | 1 | 3 | 14 | 26 | |
Expression of HNF-4α was detected using immunohistochemical staining in 126 cases of human gastric cancer tissue specimens. Association of HNF-4α with clinicopathological factors was evaluated using SPSS statistical software. HNF-4α, hepatocyte nuclear factor-4α.