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. 2017 Sep 27;14(6):7145–7152. doi: 10.3892/ol.2017.7087

Figure 2.

Figure 2.

Overexpression of miR-320 inhibits cell proliferation and invasion, and induces apoptosis in MDA-MB-231 cells. (A) The expression of miR-320 in MDA-MB-231 cells transfected with miR-320 mimics or NC. (B) Colony formation analysis of miR-320-overexpressing and NC MDA-MB-231 cells. (C) MTT analysis of miR-320-overexpressing and NC MDA-MB-231 cells. (D) The cell cycle distribution of miR-320-overexpressing and NC MDA-MB-231 cells. (E) Apoptosis analysis of miR-320-overexpressing and NC MDA-MB-231 cells. (F) Transwell invasion assay of miR-320-overexpressing and NC MDA-MB-231 cells (magnification, ×400). ##P<0.01 and ###P<0.001 vs. NC. miR, microRNA; NC, negative control; PI, propidium iodide; FITC, fluorescein isothiocyanate.