Table II.
Relationship between LMO1, Bcl-2, Bax proteins and biological characteristics of gastric cancer patients.
LMO1 | Bcl-2 | Bax | |||||||
---|---|---|---|---|---|---|---|---|---|
Biological characteristics (n) | Negative (24) | Positive (72) | χ2 (P-value) | Negative (27) | Positive (69) | χ2 (P-value) | Negative (59) | Positive (37) | χ2 (P-value) |
Sex | |||||||||
Male (66) | 17 | 49 | 0.065 (0.799) | 17 | 49 | 0.586 (0.444) | 39 | 20 | 1.393 (0.238) |
Female (30) | 7 | 23 | 10 | 20 | 20 | 17 | |||
Age, years | |||||||||
≥60 (55) | 15 | 40 | 0.355 (0.551) | 17 | 38 | 0.494 (0.482) | 36 | 19 | 0.868 (0.351) |
<60 (41) | 9 | 32 | 10 | 31 | 23 | 18 | |||
Diameter, cm | |||||||||
≥5 (58) | 14 | 44 | 0.058 (0.810) | 14 | 44 | 1.152 (0.283) | 39 | 19 | 2.069 (0.150) |
<5 (38) | 10 | 28 | 13 | 25 | 20 | 18 | |||
Serosal invasion | |||||||||
Negative (31) | 9 | 22 | 0.397 (0.529) | 13 | 18 | 4.320 (0.038) | 20 | 11 | 0.181 (0.671) |
Positive (65) | 15 | 50 | 14 | 51 | 39 | 26 | |||
TNM staging | |||||||||
I–II (28) | 11 | 17 | 4.303 (0.038) | 10 | 18 | 1.126 (0.289) | 15 | 13 | 1.038 (0.308) |
III (68) | 13 | 55 | 17 | 51 | 44 | 24 | |||
Differentiation | |||||||||
Well (67) | 16 | 51 | 0.148 (0.700) | 15 | 52 | 3.611 (0.057) | 40 | 27 | 0.289 (0.591) |
Poor (29) | 8 | 21 | 12 | 17 | 19 | 10 | |||
Lymphatic metastasis | |||||||||
Positive (71) | 13 | 58 | 6.508 (0.011) | 18 | 53 | 1.037 (0.309) | 48 | 23 | 4.350 (0.037) |
Negative (25) | 11 | 14 | 9 | 16 | 11 | 14 |
LMO1, LIM domain only 1; Bcl-2, apoptosis regulator Bcl-2; Bax, apoptosis regulator Bax; TNM, tumor node metastasis.