Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
HDAC protein accumulation in CHI-resistant lung cancer cells. (A) HDAC activity of A549 and A549-CHI-R cells. (B) Western blot analysis of HDACs with or without 5 µM CHI treatment for 72 h. (C) Protein level of HDAC1 and 2 in A549 and A549-CHI-R cells incubated with 10 µg/ml CHX for the indicated times. **P<0.005 vs. A549 cells. HDAC, histone deacetylase; CHI, chidamide; A549-CHI-R, chidamide-resistant A549 cells; CHX, cycloheximide.
