Figure 4.

Relative Th subset proportion and expression level of the Th-associated molecule AHR. (A) The frequency of Th22 was increased in ND patients relative to CR patients and normal controls. (B) The relative proportion of the Th1 subset was decreased in ND patients compared with the CR group and controls; however, no statistical significance was identified. (C) No significant difference in relative AHR expression in PBMCs was identified between the ND, CR and control groups. (D) In BMMCs, AHR was markedly increased in the ND group compared to the CR group. Th, T-helper cells; AHR, aryl hydrocarbon receptor; ND, newly diagnosed; CR, complete remission; PBMCs, peripheral blood mononuclear cells; BMMCs, bone marrow mononuclear cells.