Table 3.
Effectiveness of Maternal Tdap Vaccination at Preventing Infant Pertussis, by Timing of Vaccination
| Cases | Controls | Multivariable VEa, % (95% CI) | |||
|---|---|---|---|---|---|
| Total | 240 | % | 535 | % | |
| Unvaccinated | 104 | 43.3 | 177 | 33.1 | REFERENCE |
| Before pregnancy | 24 | 10.0 | 67 | 12.5 | 50.8 (2.1 – 75.2) |
| 1st or 2nd trimester | 5 | 2.1 | 27 | 5.1 | 64.3 (−13.8 – 88.8) |
| 3rd trimester | 17 | 7.1 | 90 | 16.8 | 77.7 (48.3 – 90.4) |
| After pregnancy | 90 | 37.5 | 174 | 32.5 | 4.9 (−49.3 – 39.5) |
Abbreviations: CI, confidence interval; VE, vaccine effectiveness
The following variables were included in the final model: household size >2 persons, maternal education, household member with pertussis diagnosis, and infant age (weeks).