Table 4.
Effectiveness of Maternal Tdap Vaccination at Preventing Infant Pertussis Hospitalizations, by Timing of Vaccination
| Cases | Controls | Multivariable VEa, % (95% CI) | |||
|---|---|---|---|---|---|
| Total | 157 | % | 336 | % | |
| Unvaccinated | 76 | 48.4 | 109 | 32.4 | REFERENCE |
| Before pregnancy | 16 | 10.2 | 46 | 13.7 | 76.2 (37.2 – 91.0) |
| 1st or 2nd trimester | 2 | 1.3 | 20 | 6.0 | 91.4 (24.8 – 99.0) |
| 3rd trimester | 6 | 3.8 | 47 | 14.0 | 90.5 (65.2 – 97.4) |
| After pregnancy | 57 | 36.3 | 114 | 33.9 | 32.5 (−23.5 – 63.1) |
Abbreviations: CI, confidence interval; VE, vaccine effectiveness
The following variables were included in the final model: household size >2 persons, maternal education, household member with pertussis diagnosis, and infant age (weeks).