Table 5.
The comparison of antimicrobial MIC between KPC gene-positive and KPC gene-negative CRKP isolates
| Items | AK | IP | MP | ETP | CPS | PTc | PM | MX | LE | TGC | CRO | TZ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P* | 0.501 | 0.126 | 0.880 | 0.370 | 0.697 | 0.373 | 0.375 | 0.143 | 0.449 | 0.309 | 0.091 | 0.961 |
| P† | 0.620 | 0.001 | 0.001 | 0.038 | 0.034 | 0.016 | 0.348 | 0.059 | 0.035 | 0.301 | 0.180 | 0.126 |
*The MIC difference between death group and survival group in KPC-gene positive isolates; †The MIC difference between KPC-gene positive group and negative group. AK: Amikacin; IP: Imipenem; MP: Meropenem; ETP: Ertapenem; CPS: Cefoperazone-sulbactam; PTc: Piperacillin-tazobactam; PM: Cefepime; MX: Moxifloxacin; LE: Levofloxacin; TGC: Tigecycline; CRO: Ceftriaxone; TZ: Ceftazidime; MIC: Minimum inhibitory concentration; KP: Klebsiella pneumoniae; KPC: KP carbapenemase; CRKP: Carbapenem-resistant KP.