Table II.
Association between EGFR, CXCR4 and MMP-9 expression and clinicopathological factors in NSCLC.
| CXCR4, n (%) | EGFR, n (%) | MMP-9, n (%) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Parameter | Low | High | P-value | Low | High | P-value | Low | High | P-value |
| Age, years | 0.142 | 0.537 | 1 | ||||||
| <60 | 10 (53) | 27 (64) | 6 (40) | 14 (30) | 7 (32) | 13 (33) | |||
| ≥60 | 9 (47) | 15 (36) | 9 (60) | 32 (70) | 15 (68) | 26 (67) | |||
| Sex | 0.266 | 0.13 | 0.416 | ||||||
| Male | 8 (42) | 28 (67) | 6 (40) | 30 (76) | 11 (50) | 25 (64) | |||
| Female | 11 (68) | 14 (33) | 9 (60) | 16 (24) | 11 (50) | 14 (36) | |||
| Tumor differentiation | 0.025 | 0.015 | 0.033 | ||||||
| Well | 10 (42) | 35 (64) | 7 (47) | 38 (61) | 20 (91) | 25 (64) | |||
| Poor | 9 (58) | 7 (36) | 8 (63) | 8 (39) | 2 (9) | 14 (36) | |||
| Lymph node metastasis | 0.002 | 0.013 | 0.008 | ||||||
| Yes | 4 (21) | 27 (64) | 5 (26) | 26 (62) | 16 (73) | 14 (36) | |||
| No | 15 (79) | 15 (36) | 14 (74) | 16 (38) | 6 (27) | 25 (64) | |||
P-values were calculated using the χ2 test. EGFR, epidermal growth factor receptor; CXCR4, CXC receptor 4; MMP-9, matrix metallopeptidase-9.