Table 1.

Alignment of WES data from the human-mouse DNA dilution series

% of human DNA	%of mouse DNA	Replicate	Alignment efficiency human genome %	Alignment efficiency combined genome (%)	%of reads mapped on the human genome	%of reads mapped on the mouse genome	Estimated human DNA content
100	0	a	90.81	90.64	99.98	0.02	99.89
100	0	b	90.38	90.16	99.98	0.02	99.88
100	0	c	90.26	90.13	99.98	0.02	99.89
90	10	a	88.57	90.43	97.59	2.41	90.22
90	10	b	88.53	90.39	97.58	2.42	90.16
50	50	a	75.65	89.37	83.14	16.86	50.73
50	50	b	74.90	89.71	82.18	17.82	49.01
50	50	c	75.41	89.55	82.78	17.22	50.07
25	75	a	58.07	89.25	62.44	37.56	23.97
25	75	b	60.25	89.48	64.58	35.42	26.17
0	100	a	7.01	88.77	0.10	99.90	0.00
0	100	b	7.17	88.56	0.10	99.90	0.00
0	100	c	6.65	88.95	0.08	99.92	0.00