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. 2018 Jan 5;17:1. doi: 10.1186/s12943-017-0753-1

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — miR-494 is overexpressed in CRC. a Hierarchical clustering of miRNA expression profiles from the Dlk1-Dio3 region obtained from 17 pairs of CRC tissues compared with adjacent, non-tumor tissues. b The miR-494 expression levels in CRC tissues and non-tumor tissues, evaluated by real-time PCR. c The expression levels of miRNA-494 in paired samples of CRC tissues and matched adjacent non-tumor tissues. (*, P < 0.05; ***, P < 0.001, Student’s t-test)