Table III.
Univariate and multivariate analyses of the associations between prognostic variables in 130 patents with colorectal carcinoma.
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Parameters | HR | 95% CI | P-value | HR | 95% CI | P-value |
| Tumoral expression of IMP3 | 0.029 | |||||
| Negative vs. positive | 11.891 | 1.606–88.074 | 0.015 | 9.356 | 1.250–70.048 | |
| TNM stage | 0.045 | |||||
| I- II vs. III -IV | 7.195 | 2.471–20.949 | <0.001 | 6.178 | 1.037–36.800 | |
| Lymph node metastasis | 0.567 | |||||
| No vs. yes | 4.068 | 1.708–9.689 | 0.002 | 0.511 | 0.051–5.0913 | |
| Lympho-vascular invasion | 0.402 | |||||
| No vs. yes | 3.973 | 1.499–10.530 | 0.006 | 0.402 | 0.358–12.913 | |
Analyses were performed using the Cox regression model. CI, confidence interval; HR, hazard ratio; IMP3, insulin-like growth factor II mRNA-binding protein 3.