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. 2017 Oct 3;14(6):7483–7488. doi: 10.3892/ol.2017.7121

Figure 3.

Figure 3.

TSLP-derived of cervical cancer cells upregulates the secretion of IL-8 and VEGF. HL-60E were co-cultured with HeLa or CaSki cells for 48 h and subsequently rhTSLP (100 ng/ml), α-TSLP (5 ug/ml) or α-TSLPR (5 ug/ml) was added for an additional 48 h. The secretion level of (A) IL-8, (B) VEGF and (C) FGF were determined using ELISA. The data are expressed as the mean ± standard error of the mean. *P<0.05, **P<0.01 or ***P<0.001 vs. CO of HL-60E with HeLa cells control, determined using a one-way analysis of variance; #P<0.05 or ###P<0.001 vs. CO of HL-60E with CasKi cells control, determined using a one-way analysis of variance. CO, co-culture group (HL-60E with HeLa or CaSki cells); TSLP, thymic stromal lymphopoietin; α-TSLP, anti-human TSLP neutralizing antibody; α-TSLPR, anti-human TSLP receptor neutralizing antibody.