Table 3.
Multivariate logistic regression analysis of risk factors to predict major LEA in the patients with infectious foot gangrene
| Factors+ | Interpretation | Odds ratio | 95% confidence interval | P value |
|---|---|---|---|---|
| Abnormal ABI | Yes vs. No | 3.12* | 1.18–8.24 | 0.02 |
| Age | Every 1 year increment | 0.97 | 0.93–1.02 | 0.21 |
| Diabetes duration | Every 1 year increment | 0.99 | 0.94–1.04 | 0.66 |
| Smoking status | Yes vs. No | 0.54 | 0.19–1.53 | 0.25 |
| Hypertension | Yes vs. No | 1.28 | 0.53–3.10 | 0.59 |
| MACE history | Yes vs. No | 1.13 | 0.45–2.80 | 0.80 |
| CKD (eGFR < 60) | vs. normal renal function (eGFR ≥60) | 1.81 | 0.74–4.46 | 0.20 |
| Dialysis | vs. normal renal function (eGFR ≥60) | 2.51 | 0.71–8.85 | 0.15 |
| HbA1c | Every 1% increment | 0.95 | 0.81–1.13 | 0.58 |
*Significance: P value <0.05
+Including the continuous variable of age, diabetes duration and HbA1c; and categorical variables of smoking status, hypertension, major adverse cardiac events, ankle-brachial index, and renal function
LEA lower-extremity amputation, ABI ankle-brachial index, MACE major adverse cardiac event, CKD chronic kidney disease, eGFR estimated glomerular filtration rate