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. Author manuscript; available in PMC: 2018 Jan 5.
Published in final edited form as: Thromb Haemost. 2017 Apr 6;117(7):1402–1411. doi: 10.1160/TH16-05-0373

Figure 1. Influence of treatment of RBCs with the LAT inhibitors BCH and L-leucine (L-Leu) on RBC-EC adhesion as a function of shear stress.

Figure 1

The adhesion of fresh human RBCs to HUVECs exposed or not to BCH or L-Leu was quantified in customized flow chambers at varying shear stress. One set of individual adhesion curves is shown in (A) and the mean results from n=4–9 experiments at 1, 2, or 5 dynes/cm2 (B, BCH) and (C, L-Leu). *, p<0.05 vs. Con (vehicle control) by paired t-test. #, p=0.0002 for comparison of full Con vs. BCH curves; ##, p = 0.0021 for Con vs. Leu curves (two-way ANOVA).