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. Author manuscript; available in PMC: 2018 Jan 5.
Published in final edited form as: Thromb Haemost. 2017 Apr 6;117(7):1402–1411. doi: 10.1160/TH16-05-0373

Figure 2. Influence of the LAT1-specific inhibitor JPH-203 on RBC-EC adhesion as a function of shear stress.

Figure 2

The adhesion to HUVECs of fresh human RBCs exposed or not to JPH-203 (50 nM) was quantified in customized flow chambers at varying shear stress. JPH-203 (50 nM) was also included in the perfusion medium. One set of individual adhesion curves is shown in (A) and the mean results from n=5 experiments each at 1, 2, or 5 dynes/cm2 in (B). *, p<0.05 vs. Con (vehicle control) by paired t-test; comparison of Con vs. JPH-203 curves is by two-way ANOVA.