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. Author manuscript; available in PMC: 2018 Jan 5.
Published in final edited form as: Thromb Haemost. 2017 Apr 6;117(7):1402–1411. doi: 10.1160/TH16-05-0373

Figure 6. Pulmonary responses in nude mice to transfusion of fresh human RBCs treated or not with the LAT inhibitors L-Leu or BCH.

Figure 6

(A) Individual blood oxygenation tracings and (B) mean (± SEM; n=4) data are shown. The indicated p-values are for paired t-tests. Responses to RBCs stored 37–42 days are also shown. RBC transfusate exposure to either LAT inhibitor tended to promote transfused-RBC sequestration within the lungs, as seen in fluorescence photomicrographs (C,D); mean data for fluorescence intensity are summarized in (E). p=0.2169 for Con vs. BCH, and p=0.0583 for Con vs. Leu by paired t-test. n=4 pairs in lung images and n=6 pairs for blood oxygenation means.