Figure 1.

The hepatic immune cells. Schematic representation showing hepatic cells and their location. The liver harbors a large population of immune cells. Dendritic cells (CX3CR1⁺ cells) can be found in the subcapsular space and surround large vessels, as the centrilobular vein and the portal triade vessels (portal vein and hepatic artery). Kupffer cells are the liver resident macrophages and constitute the largest population of hepatic immune cells. They can be found within sinusoids, in contact with endothelial cells. Neutrophils, B lymphocytes, T lymphocytes, and NK cells eventually circulate in the sinusoids.