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. Author manuscript; available in PMC: 2018 Jan 5.
Published in final edited form as: J Biomed Inform. 2010 May 11;44(1):8–25. doi: 10.1016/j.jbi.2010.04.008

Table 2.

Examples from the SIOP Trial for CRF questions and ontological paths. Note that for multiselection items the chairperson can select from the subclasses of the specified class all classes she wants to provide as multiple-choice items.

Question on CRF Ontological path Question type
“Is the patient undergoing treatment as part of a clinical trial protocol he/she is enrolled in?” Patient undergoes TherapeuticProcess implements ClinicalTrialProtocol Exist
“What is the tumor structure of the tumor in the patient’s kidney?” Patient hasPart Kidney has Part Neoplasm hasQuality TumorHomogeneity Multiselection with answer possibilities x, y and z Value
“At what date does radiotherapy start for the patient?” Patient undergoes Radiotherapy hasDate Date