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. Author manuscript; available in PMC: 2019 Jan 30.
Published in final edited form as: Gene. 2017 Oct 21;641:220–225. doi: 10.1016/j.gene.2017.10.063

Fig. 5.

Fig. 5

Regulation of Kv11.1 isoform expression by modified U1 snRNA in canonical poly(A) signal construct. (A) RPA analysis of mRNA from Flp-In CV-1 cells stably expressing the full-length KCNH2 splicing-competent construct containing the canonical poly(A) signal following the treatment with WT or modified U1 snRNA adenovirus. (B) RPA signals were quantified, normalized to hygromycin resistance gene (Hygro), and plotted as the relative expression of the total uninfected (1a+1a-USO) Kv11.1 mRNA (n=3, *P < 0.05, **P < 0.01).