Table 3.
Breast Cancer-Specific Survival (BCSS) and Overall survival (OS) by approximated clinical tumor subtype and pathologic response
| pCR | Residual Disease | ||||||
|---|---|---|---|---|---|---|---|
| HR pos/HER2 neg | HER2 positive | Triple negative | HR pos/HER2 neg | HER2 positive | Triple negative | ||
| BCSS | |||||||
| HR | 1.00 | — | — | 1.00 | 0.11 | 2.35 | |
| 95% CI | ref | — | — | ref | 0.03 – 0.44 | 1.50 – 3.68 | |
| 5 yr | 100% | 96.0% | 89.8% | 78.3% | 95.8% | 65.8% | |
| p value | 0.018 | <0.0001 | |||||
| OS | |||||||
| HR | 1.00 | 1.14 | 4.02 | 1.00 | 0.32 | 2.18 | |
| 95% CI | ref | 0.12 – 10.96 | 0.50 – 32.71 | ref | 0.15 – 0.71 | 1.42 – 3.34 | |
| 5 yr | 97.1% | 94.6% | 87.8% | 74.4% | 92.8% | 64.4% | |
| p value | 0.086 | <0.0001 | |||||
Abbreviations: pCR = Pathologic complete response.