Table 2. Incidence of dementia and Cox model results for the ARD patient group and the comparison group.
| Comparison group | ARD patient group | |||||
|---|---|---|---|---|---|---|
| Characteristics | Event (%) | Incidence§ | Event (%) | Incidence§ | IRR | Adjusted HRa (95% CI) |
| All | 4280(3.09) | 48.43 | 1305 (3.77) | 63.08 | 1.30 | 1.18 (1.11–1.26)*** |
| Sex | ||||||
| Female | 3211 (3.00) | 46.75 | 969 (3.62) | 59.58 | 1.27 | 1.18 (1.10–1.27)*** |
| Male | 1069 (3.40) | 54.30 | 336 (4.27) | 75.94 | 1.40 | 1.23 (1.09–1.40)** |
| Age | ||||||
| <65 | 828 (0.86) | 12.98 | 259 (1.07) | 16.81 | 1.30 | 1.06 (0.92–1.22) |
| 65–74 | 1894 (6.57) | 107.23 | 567 (7.87) | 145.00 | 1.35 | 1.20 (1.09–1.32)*** |
| ≥75 | 1558 (11.91) | 225.59 | 479 (14.65) | 349.00 | 1.55 | 1.26 (1.13–1.40)*** |
| Diabetes | ||||||
| No | 3164 (2.62) | 40.53 | 985 (3.33) | 54.82 | 1.35 | 1.21 (1.12–1.30)*** |
| Yes | 1116 (6.20) | 108.15 | 320 (6.35) | 117.57 | 1.09 | 1.06 (0.94–1.21) |
| Hyperlipidemia | ||||||
| No | 3408 (2.87) | 44.33 | 1061 (3.67) | 60.96 | 1.38 | 1.23 (1.14–1.32)*** |
| Yes | 872 (4.43) | 75.87 | 244 (4.23) | 74.28 | 0.98 | 1.00 (0.87–1.16) |
| Psychosis | ||||||
| No | 3962 (2.93) | 45.79 | 1164 (3.50) | 58.40 | 1.28 | 1.20 (1.12–1.28)*** |
| Yes | 318 (9.56) | 171.32 | 141 (9.94) | 186.48 | 1.09 | 1.06 (0.87–1.30) |
| Hypertension | ||||||
| No | 1912 (1.91) | 29.10 | 568 (2.52) | 40.55 | 1.39 | 1.32 (1.20–1.45)*** |
| Yes | 2368 (6.17) | 104.50 | 737 (6.08) | 110.31 | 1.06 | 1.05 (0.97–1.14) |
| Stroke | ||||||
| No | 3437 (2.61) | 40.55 | 1050 (3.26) | 53.95 | 1.33 | 1.26 (1.18–1.35)*** |
| Yes | 843 (12.53) | 232.47 | 255 (10.25) | 207.99 | 0.89 | 0.90 (0.78–1.04) |
| Traumatic brain injury | ||||||
| No | 4158 (3.04) | 47.61 | 1247 (3.65) | 61.07 | 1.28 | 1.17 (1.10–1.25)*** |
| Yes | 122 (7.13) | 117.10 | 58 (11.35) | 214.73 | 1.83 | 1.60 (1.16–2.21)** |
| Cardiovascular disease | ||||||
| No | 2731 (2.36) | 36.49 | 649 (2.84) | 46.08 | 1.26 | 1.29 (1.18–1.40)*** |
| Yes | 1549 (6.81) | 114.43 | 656 (5.57) | 99.33 | 0.87 | 1.03 (0.94–1.13) |
§ Incidence per 10,000 person-years
*: p value for HR < 0.05
**: p value for HR < 0.01
***: p value for HR < 0.001
a HR adjusted by age group, sex, and comorbidities