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. 2017 Dec 8;10:130–142. doi: 10.1016/j.dadm.2017.11.007

Table 1.

The major goals of the WRAP study

  • 1

    Determine whether AD-related cognitive trajectories can be detected in midlife and distinguished from normal aging using sensitive cognitive assessments.

  • 2

    Determine the effect of genetic vulnerability on AD-related cognitive trajectories and biomarkers.

  • 3

    Determine the biomarker patterns associated with cognitive trajectories and the development of symptomatic cognitive dysfunction.

  • 4

    Examine the influence of health behaviors on risk and resilience to brain pathology and cognitive decline due to AD.

Abbreviations: WRAP, Wisconsin Registry for Alzheimer's Prevention; AD, Alzheimer's disease.