Table 4. Number of maternal STIs (chlamydia, gonorrhea, syphilis, CMV) Frequency distribution by infant HIV-infection status.
| Infant HIV-infected (N = 82) |
Infant HIV-uninfected (N = 817) |
p-value* (for total only) | |
|---|---|---|---|
| n (col %) | n (col %) | n (col %) | |
| 0.003 | |||
| 0 STI (n = 626) | 47 (57.3) | 579 (70.9) | |
| 1 STI (n = 223) | |||
| TP | 6 (7.3) | 50 (6.1) | |
| CT | 9 (12) | 109 (13.3) | |
| NG | 11 (1.4) | ||
| CMV | 9 (11) | 29 (3.6) | |
| Total | 24 (29.3) | 199 (24.4) | |
| 2 STIs (n = 42) | |||
| CT, NG | 3 (3.7) | 13 (1.6) | |
| CT, TP | 2 (2.4) | 8 (1.0) | |
| CT, CMV | 5 (6.1) | 3 (1.3) | |
| NG, TP | 2 (0.2) | ||
| TP, CMV | 6 (0.7) | ||
| Total | 10 (12.2) | 32 (3.9) | |
| 3 STIs (n = 8) | |||
| CT, TP, CMV | 1 (0.1) | ||
| CT, NG, CMV | 1 (1.2) | 3 (0.4) | |
| CT, NG, TP | 3 (0.4) | ||
| Total | 1 (1.2) | 7 (0.9) |
* P-value was generated by the Chi-square test to compare the proportion of STI infections (0 STI vs 1 STI vs 2 STIs vs 3 STIs) between HIV-infected and HIV-uninfected infants.
Abbreviations: CMV, cytomegalovirus and specifically refers to infant congenital CMV here; CT = Chlamydia trachomatis; HIV, human immunodeficiency virus; NG = Neisseria gonorrhoeae; STI = sexually transmitted infection; TP = Treponema pallidum (syphilis).