Table 3. Effects of NICU-related stress and SLC6A4 methylation on brain volumes.
| Predictors | Outcome Variables | |||||||
|---|---|---|---|---|---|---|---|---|
| Anterior Temporal Lobe—Medial Part | ||||||||
| ATL-MPR | ATL-MPL | |||||||
| B | SE | t | p | B | SE | t | p | |
| Gestational age at birth | .00 | .15 | -.03 | .98 | -.10 | .15 | -.66 | .51 |
| NICU-related stress | -.06 | .31 | -.20 | .84 | -.08 | .30 | -.26 | .80 |
| Δmet | -.48 | .16 | -3.06 | .01 | -.54 | .15 | -3.50 | .00 |
| SES | .01 | .01 | .63 | .54 | .01 | .01 | .92 | .37 |
| Gestational age at MRI | .11 | .21 | .54 | .59 | .24 | .20 | 1.16 | .26 |
| ATL-LPR | ATL-LPL | |||||||
| B | SE | t | p | B | SE | t | p | |
| Gestational age at birth | -.17 | .15 | -1.15 | .26 | -.28 | .15 | -1.85 | .08 |
| NICU-related stress | -.20 | .31 | -.64 | .53 | -.33 | .31 | -1.07 | .30 |
| Δmet | -.44 | .16 | -2.76 | .01 | -.37 | .16 | -2.32 | .03 |
| SES | .01 | .01 | .73 | .47 | .01 | .01 | 1.00 | .33 |
| Gestational age at MRI | .43 | .21 | 2.02 | .06 | .53 | .21 | 2.55 | .02 |
Note. ATL-MPR, anterior temporal lobe–medial part right; ATL-MPL, anterior temporal lobe–medial part left; ATL-LPR, anterior temporal lobe–lateral part right; ATL-LPL, anterior temporal lobe–lateral part left; NICU, Neonatal Intensive Care Unit; Δmet, mean change in SLC6A4 methylation from birth to NICU discharge at CpG chr17: 28562786–28562787; SES, socio-economic status; MRI, magnetic resonance imaging.