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. 2018 Jan 5;13(1):e0190628. doi: 10.1371/journal.pone.0190628

Fig 4. Effects of soluble guanylate cyclase stimulation on the regulation of apoptosis.

Fig 4

Guinea pigs were exposed to either cigarette smoke (CS) or sham for 3 months, and received either the sGC stimulator (BAY 41–2272) or vehicle only. (A) Protein expression of BAX was measured by western blot (A and B) and immunohistochemistry (C). Statistical differences in western blotting results were analyzed by 2-way ANOVA. Pairwise multiple comparisons between the individual groups were performed using the Holm–Šidák method.