Table 1. Clinical variables of the 112 hemodialysis patients with high or low arterial stiffness.
Characteristics | All Patients (n = 112) | Low Arterial Stiffness Group (n = 74) | High Arterial Stiffness Group (n = 38) | P |
---|---|---|---|---|
Age (years) | 62.54 ± 13.52 | 60.54 ± 13.48 | 66.42 ± 12.92 | 0.029* |
HD duration (years) | 4.63 (1.80–10.32) | 4.74 (1.79–11.21) | 4.55 (1.86–6.92) | 0.325 |
Post-HD body weight (Kg) | 61.91 ± 14.90 | 59.80 ± 15.28 | 66.02 ± 13.39 | 0.036* |
Waist circumference (cm) | 91.35 ± 13.06 | 88.77 ± 12.88 | 96.37 ± 12.05 | 0.003* |
Body mass index (Kg/m2) | 24.10 ± 4.96 | 23.31 ± 5.02 | 25.64 ± 4.52 | 0.018* |
Body fat mass (%) | 27.73 ± 6.51 | 25.79 ± 6.55 | 31.49 ± 4.54 | 0.001* |
Carotid-femoral PWV (m/s) | 9.49 ± 3.42 | 7.52 ± 1.58 | 13.32 ± 2.71 | <0.001* |
Aortic SBP (mmHg) | 131.47 ± 26.76 | 129.88 ± 28.37 | 134.58 ± 23.36 | 0.381 |
Aortic DBP (mmHg) | 78.60 ± 16.36 | 79.80 ± 17.86 | 76.26 ± 12.86 | 0.281 |
WBC (x1000/uL) | 6.36 ± 2.05 | 6.11 ± 1.99 | 6.85 ± 2.10 | 0.071 |
Hemoglobin (g/dL) | 10.38 ± 1.17 | 10.22 ± 1.25 | 10.70 ± 0.92 | 0.040* |
Iron (μg/dL) | 68.02 ± 26.09 | 66.89 ± 26.12 | 70.21 ± 26.24 | 0.526 |
Total iron-binding capacity (μg/dL) | 263.55 ± 47.30 | 269.46 ± 51.62 | 252.05 ± 35.35 | 0.065 |
Ferritin (ng/mL) | 208.50 (90.73–400.48) | 221.55 (75.88–409.35) | 201.70 (151.25–365.38) | 0.549 |
Total cholesterol (mg/dL) | 146.69 ± 36.21 | 144.68 ± 38.15 | 150.61 ± 32.23 | 0.414 |
Triglyceride (mg/dL) | 126.50 (87.50–199.50) | 108.50 (80.00–198.50) | 157.00 (114.75–217.75) | 0.010* |
Glucose (mg/dL) | 132.00 (109.25–175.75) | 130.00 (106.75–163.50) | 140.00 (109.75–222.00) | 0.090 |
Blood urea nitrogen (mg/dL) | 59.60 ± 13.97 | 59.95 ± 14.42 | 58.92 ± 13.21 | 0.715 |
Creatinine (mg/dL) | 9.37 ± 1.90 | 9.46 ± 2.03 | 9.19 ± 1.60 | 0.478 |
Total calcium (mg/dL) | 8.93 ± 0.75 | 8.85 ± 0.73 | 9.08 ± 0.77 | 0.133 |
Phosphorus (mg/dL) | 4.65 ± 1.28 | 4.66 ± 1.37 | 4.64 ± 1.11 | 0.942 |
Intact parathyroid hormone (pg/mL) | 204.05 (71.48–373.78) | 225.50 (92.48–363.05) | 165.85 (51.88–422.90) | 0.452 |
Leptin (ng/mL) | 16.53 (6.36–44.39) | 8.47 (3.74–25.55) | 66.08 (20.37–92.71) | <0.001* |
Urea reduction rate | 0.73 ± 0.05 | 0.73 ± 0.05 | 0.74 ± 0.04 | 0.976 |
Kt/V (Gotch) | 1.34 ± 0.18 | 1.35 ± 0.19 | 1.34 ± 0.17 | 0.826 |
Values for continuous variables given as means ± standard deviation and test by Student’s t-test; variables not normally distributed given as medians and interquartile range and test by Mann-Whitney U test. HD, hemodialysis; SBP, systolic blood pressure; DBP, diastolic blood pressure; WBC, white blood cell; Kt/V, fractional clearance index for urea.
* P< 0.05 was considered statistically significant.