Skip to main content
. 2018 Jan 5;13(1):e0191032. doi: 10.1371/journal.pone.0191032

Fig 3. Effects of adrenoceptor agonists on capsaicin currents.

Fig 3

(A) Typical responses to capsaicin (1 μM) in the absence and presence of clonidine (1 pM) are shown. (B) Yohimbine (1 nM) was applied in combination with clonidine (1 pM) in the same protocol as A. Dashed lines in panels A, B indicate zero current level. (C) The relative peak amplitudes of capsaicin currents by the second stimulation compared to those by the first stimulation in each neuron are shown (2nd/1st response). Amplitudes of capsaicin currents in the presence of dexmedetomidine (1 pM) and isoproterenol (1 pM) are also shown. The columns and vertical bars indicate the mean ± SEM (n = 9, 10, 5, 4 and 4 from the left). * P < 0.05 against the control data in the absence of adrenergic agonists.