Table 1. Clinical characteristics and lipid profiles of healthy subjects and CETP-D patients.
| healthy subjects | CETP-D patients | p value | |
|---|---|---|---|
| Age (year) | 57.6±14.8 | 56.7±15.5 | 0.90 |
| Sex (m/f) | 4/5 | 4/5 | |
| TC (mg/dL) | 205.7±29.6 | 313.9±104.9 | 0.009 |
| TG (mg/dL) | 99.7±26.2 | 109.6±84.2 | 0.73 |
| HDL-C (mg/dL) | 60.0±8.1 | 162.2±44.9 | <0.001 |
| LDL-C (mg/dL) | 112.7±21.8 | 51.4±11.8 | <0.001 |
| FC (mg/dL) | 50.2±8.6 | 82.7±24.4 | 0.002 |
| PL (mg/dL) | 227.1±29.1 | 351.6±107.6 | 0.004 |
| Apolipoprotein A-I (mg/dL) | 152.8±19.6 | 245.0±59.6 | <0.001 |
| Apolipoprotein A-II (mg/dL) | 29.9±2.8 | 39.1±9.9 | 0.016 |
| Apolipoprotein B (mg/dL) | 93.3±16.1 | 75.3±13.7 | 0.02 |
| Apolipoprotein C-II (mg/dL) | 4.4±1.0 | 7.6±2.9 | 0.007 |
| Apolipoprotein C-III (mg/dL) | 9.9±2.2 | 28.2±18.1 | 0.009 |
| Apolipoprotein E (mg/dL) | 4.5±1.0 | 14.1±5.8 | <0.001 |
| CETP mass (μg/mL) | 3.1±0.8 | <0.1 | <0.001 |
TC, total cholesterol; TG, triglyceride; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; FC, free cholesterol; PL, phospholipid. Data are shown as the mean ± SD and statistical significance was calculated by unpaired Student's T test.