Table 8. Contribution of chemical signals to CO₂/H⁺ sensitivity in each channel.

weight/current	KA	Kdr	Kir	CaT	CaL	BK	KLeak
wpHi	0.3	1	1	0	0	1	0.5
wpHo	0.7	0	0	1	0.3	0	0.5
wCO2	0	0	0	0	0.7	0	0

Channel-specific weights assigned to each signal. Intracellular pH, w_pHi,, extracellular pH, w_pH0, and CO₂ level, w_CO2. For non-chemosensitive currents the weight is set to zero. These values were adjusted to fit percentage of activation/inactivation of specific currents in different acidotic challenges [23,45,47,49]. Abbreviations for currents as in Eq 2.