Table 9. Signal values at midpoint current inhibition/or activation.
| S1/2/current | KA | Kdr | Kir | CaT | CaL | BK | KLeak |
|---|---|---|---|---|---|---|---|
| pKi | 7.4 | 7.1 | 7 | --- | --- | 6.5 | 7.3 |
| pKo | 7.3 | --- | --- | 6.9 | 6.5 | --- | 7.4 |
| (CO2)½ | --- | --- | --- | --- | 5 | --- | --- |
Midpoint values for current inhibition/activation curves. A pK value was assigned to intracellular (pKi) and extracellular (pKo) pH titration curves. The percentage of CO2 required to achieve half-maximal current activation, (CO2)½ was calculated as an approximation to fit data from ref [19]. Abbreviations for currents as in Eq 2.