Figure 3.

XN (0.8 mg/kg) treatment preserves mouse retinal function following toxic light exposure. Scotopic ERG a-wave (A) and b-wave (B) amplitudes measured at 2 weeks following toxic light exposure. Mice injected with vehicle and exposed to 50,000-lux light for 6 hours exhibit the greatest reduction in a- and b-wave amplitudes. Mice treated with XN and exposed to toxic light show moderate a-wave preservation, while b-waves are more preserved. For each group n = 3, *P < 0.05 versus all other groups.