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. 2018 Jan;59(1):45–53. doi: 10.1167/iovs.17-22132

Figure 7.

Figure 7

XN treatment decreases the number of TUNEL-positive cells following toxic light exposure. Groups of XN- and vehicle-treated mice received toxic light exposure and were euthanized immediately, 6 hours, or 24 hours after exposure. Retinas were collected, sectioned, and used for a TUNEL assay. XN-treated mice exhibited significantly fewer TUNEL-positive cells compared to the vehicle-treated group at both 6 hours and 24 hours post-toxic light exposure (*P < 0.0001 vs. other groups; Student's t-test, error bars represent SEM). Lower panels are representative images of retinal sections used in quantification.