Table 4.
Multivariable Cox regression model for one-year post-transplant mortality, adjusted for region as well as donor, recipient, and transplant parameters.
| MELD ≥ 35 | MELD < 35 | |
|---|---|---|
|
| ||
| HR (95% CI) | HR (95% CI) | |
|
| ||
| Share 35 | 0.69 (0.60–0.80) | 0.98 (0.89–1.07) |
|
| ||
| Recipient condition at time of transplant (Ref: Not hospitalized) | ||
| Hospitalized in ICU | 1.80 (1.40–2.30) | 2.23 (1.85–2.68) |
| Hospitalized, not in ICU | 1.18 (0.92–1.51) | 1.36 (1.19–1.54) |
|
| ||
| Prior liver transplantation | 1.62 (1.27–2.06) | 1.95 (1.58–2.42) |
|
| ||
| Recipient age (per 10-year increase) | 1.21 (1.13–1.29) | 1.28 (1.21–1.35) |
|
| ||
| BiochemicalMELD at LT (per 5-unit increase) | 1.00 (0.95–1.06) | 1.09 (1.04–1.13) |
|
| ||
| Donor age (per 10-year increase) | 1.08 (1.02–1.14) | 1.05 (1.02–1.09) |
|
| ||
| DCD liver | 1.78 (1.24–2.55) | 1.32 (1.10–1.58) |
|
| ||
| Cold ischemia time (per 1 hour) | 1.02 (1.00–1.05) | 1.03 (1.02–1.05) |
In addition to the variables listed, modelsincorporated donor sex, donor race, donor height, donor hepatitis C antibody or hepatitis B core antibody positive, donor hypertension, donor diabetes, donor ALT, split or partial liver transplantation, simultaneous liver-kidney transplantation, share type, region, and distance from transplant center, as well as recipient sex, race, MELD, BMI, etiology of liver disease, diabetes, dialysis at the time of transplant, exception case, exception points for HCC, portal vein thrombosis, and history of abdominal surgery.