Table 1.
Clinical Characteristics of the Studied Population
| Patient No. | Gender | Age | Primary Tumor | PLRT Total Dose | Enrollment Reason Code | Irradiation Site | Radiation Related Toxicities | Concurrent Therapy | Time Interval from the Last Radiotherapy | Total Dose of the Last Radiotherapy |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | M | 46 | Head and neck cancer | 60 Gy/30 f | Reirradiation | Locally recurrent disease | Grade 1 bone marrow suppression Grade 2 stomatitis |
Chemotherapy | 50 months | 70 Gy |
| 2 | F | 26 | Lung cancer | 50 Gy/25 f | Reirradiation | Locally recurrent disease | Grade 1 pneumonitis | Chemotherapy | 22 months | 60 Gy |
| 3 | M | 67 | Lung cancer | 56 Gy/28 f | Poor performance status | Primary tumor | Grade 1 bone marrow suppression | Chemotherapy | NA | |
| 4 | M | 74 | Lung cancer | 50 Gy/25 f | Reirradiation | Locally recurrent disease | None | None | 24 months | 59.4 Gy |
| 5 | M | 78 | Cholangiocarcinoma | 54 Gy/27 f | Poor performance status | Primary tumor | None | Adoptive immune cell therapy | NA | |
| 6 | F | 50 | Posterior peritoneal adenocarcinoma | 50 Gy/25 f | Bulky tumor | Primary tumor | Grade 1 diarrhea | Chemotherapy | NA | |
| 7 | F | 61 | Colorectal cancer | 40 Gy/20 f | Poor performance status | Primary tumor | Grade 2 nausea and vomiting | None | NA | |
| 8 | F | 75 | Colorectal cancer | 50 Gy/25 f | Re-irradiation | Locally recurrent disease | None | None | 30 months | 39 Gy |
| 9 | M | 48 | Colorectal cancer | 50 Gy/25 f | Poor performance status | Primary tumor | Grade 3 bone marrow suppression | None | NA | |
| 10 | M | 61 | Glioma | 50 Gy/25 f | Reirradiation | Locally recurrent disease | Mild brain swelling | Targeted therapy | 60 months; 12 months | 56 Gy; 60 Gy |
| 11 | M | 28 | Glioma | 48 Gy/24 f | Reirradiation | Locally recurrent disease | None | None | 36 months | 64 Gy |
| 12 | F | 52 | Bladder cancer | 2 Gy × 20 f | Bulky tumor | Primary tumor | Grade 2 bone marrow suppression Grade 2 diarrhea |
Chemotherapy | NA | |
| 13 | M | 51 | Esophageal cancer | 50 Gy/25 f | Reirradiation | Locally recurrent disease | None | None | 30 months | 60 Gy |
| 14 | M | 63 | Esophageal cancer | 60 Gy/30 f | Bulky tumor | Primary tumor | Grade 3 bone marrow suppression | Chemotherapy | NA | |
| 15 | M | 74 | Esophageal cancer | 50 Gy/25 f | Reirradiation | Locally recurrent disease | None | None | 52 months | 54gy |
| 16 | F | 52 | Gastric cancer | 50 Gy/25 f | Poor performance status | Retroperitoneal adenopathy | None | None | NA | |
| 17 | F | 36 | Gastric cancer | 2 Gy × 25 f | Poor performance status | Retroperitoneal adenopathy | Grade 1 diarrhea Grade 2 bone marrow suppression |
Chemotherapy | NA | |
| 18 | F | 70 | Gastric cancer | 44 Gy/22 f | Poor performance | Retroperitoneal adenopathy | Grade 4 bone marrow suppression Grade 3 enteritis |
Chemotherapy | NA | |
| 19 | F | 67 | Gastric cancer | 50 Gy/25 f | Poor performance status | Retroperitoneal adenopathy | Grade 3 bone marrow suppression | Chemotherapy | NA | |
| 20 | M | 79 | Gastric cancer | 60 Gy/30 f | Poor performance status | Retroperitoneal adenopathy | None | Targeted therapy | NA | |
| 21 | M | 66 | Gastric cancer | 50 Gy/25 f | Poor performance status | Retroperitoneal adenopathy | None | Chemotherapy | NA | |
| 22 | M | 52 | Chondrosarcoma | 54 Gy/27 f | Re-irradiation | Locally recurrent disease | None | None | 168 months | 50 Gy |
NA, not applicable.