Table 3.
Prospective associations between Wave 1 cannabis use and increase or decrease in nonmedical prescription opioid use at Wave 2 among adults with Wave 1 nonmedical prescription opioid use in the NESARCA
| Wave 1 any past year cannabis use predicting | Percent with Change | Odds Ratio | 95% CI | Adjusted Odds RatioB | 95% CI% | |
|---|---|---|---|---|---|---|
| Cannabis Use % | No Cannabis Use % | |||||
| Adults with Wave 1 nonmedical opioid use | (N=203) | (N=332) | ||||
| Increase opioid use at Wave 2 | 5.15 | 0.97 | 5.57 | 1.47–21.11 | 3.13 | 1.19–8.23 |
| Decrease opioid use at Wave 2 | 81.27 | 93.70 | 0.29 | 0.14–0.61 | 0.42 | 0.19–0.91 |
| Adults with Wave 1 nonmedical opioid use and painC | (N=60) | (N=105) | ||||
| Increase opioid use at Wave 2 | 7.78 | 1.97 | 4.20 | 0.64–27.50 | 2.60 | 0.42–16.05 |
| Decrease opioid use at Wave 2 | 79.97 | 93.04 | 0.30 | 0.10–0.86 | 0.60 | 0.18–2.03 |
A
NESARC denotes National Epidemiologic Survey on Alcohol and Related Conditions.
B
Adjusted for age, sex, race/ethnicity, other substance use disorders, any mood or anxiety disorder and family history of drug use disorder, alcohol use disorder, depression, and antisocial personality disorder at Wave 1.
C
Pain denotes pain with moderate to extreme interference in the last 2 weeks.