Fig. 6.

Molecular classification of glioneuronal tumours. Glioneuronal tumours can be classified into two groups based on their molecular profiles. These groups are only partially consistent with existing histological classification. Group 1 tumours are enriched for BRAF mutations and possess an astrocytic expression phenotype. In addition, they present with seizures significantly earlier. In contrast, Group 2 tumours are enriched for FGFR1 mutations and possess an oligodendrocyte precursor expression phenotype