Table 7.
Gene Set | Size | ES | NES | p value | q value |
---|---|---|---|---|---|
Group 1 vs Control | |||||
ASTROCYTE | 149 | 0.68 | 2.98 | < 0.0005 | < 0.0005 |
MICROGLIA | 148 | 0.62 | 2.72 | < 0.0005 | < 0.0005 |
ENDOTHELIA | 148 | 0.59 | 2.57 | < 0.0005 | < 0.0005 |
MO | 149 | − 0.73 | − 3.31 | < 0.0005 | < 0.0005 |
NFO | 148 | − 0.69 | − 3.13 | < 0.0005 | < 0.0005 |
NEURON | 148 | − 0.53 | − 2.40 | < 0.0005 | < 0.0005 |
OPC | 149 | − 0.32 | − 1.47 | 0.005 | 0.005 |
Group 2 vs Control | |||||
ENDOTHELIA | 149 | 0.71 | 3.06 | < 0.0005 | < 0.0005 |
MICROGLIA | 148 | 0.61 | 2.64 | < 0.0005 | < 0.0005 |
OPC | 149 | 0.61 | 2.64 | < 0.0005 | < 0.0005 |
ASTROCYTE | 149 | 0.39 | 1.68 | < 0.0005 | 0.001 |
MO | 149 | − 0.63 | − 2.71 | < 0.0005 | < 0.0005 |
NEURON | 148 | − 0.61 | − 2.53 | < 0.0005 | < 0.0005 |
NFO | 148 | − 0.46 | − 1.96 | < 0.0005 | < 0.0005 |
Group 1 vs Group 2 | |||||
ASTROCYTE | 149 | 0.61 | 2.74 | < 0.0005 | < 0.0005 |
NEURON | 148 | 0.40 | 1.76 | < 0.0005 | < 0.0005 |
MO | 149 | − 0.37 | − 1.64 | < 0.0005 | < 0.0005 |
NFO | 148 | − 0.52 | − 2.28 | < 0.0005 | < 0.0005 |
ENDOTHELIA | 149 | − 0.52 | − 2.32 | < 0.0005 | < 0.0005 |
OPC | 149 | − 0.72 | − 3.22 | < 0.0005 | < 0.0005 |
ES enrichment score. NES normalised enrichment score. For these scores, the highest and lowest scores are the most strongly enriched within each of the groups being compared, respectively. MO mature oligodendrocyte. NFO newly formed oligodendrocyte. OPC oligodendrocyte precursor cell