Fig. 8.

Cytotoxic activity of combined antimicrobial agents (AgNPs and antibacterial antibiotics) against a mouse fibroblasts (3T3) and b HeLa cell line. Both antimicrobials were used at concentrations of their FIC (see Table 2): (1) (4 µg ml⁻¹ of AgNPs + 64 µg ml⁻¹ AMP or 32 µg ml⁻¹ K or 4 µg ml⁻¹ TE), (2) (16 µg ml⁻¹ of AgNPs + 64 µg ml⁻¹ AMP or 12 µg ml⁻¹ K or 2 µg ml⁻¹ TE), (3) (1 µg ml⁻¹ of AgNPs + 768 µg ml⁻¹ AMP or 128 µg ml⁻¹ K or 64 µg ml⁻¹ TE), (4) (16 µg ml⁻¹ of AgNPs + 0.06 µg ml⁻¹ AMP or 0.5 µg ml⁻¹ K or 0.25 µg ml⁻¹ TE), (5) (4 µg ml⁻¹ of AgNPs + 0.004 µg ml⁻¹ AMP or 0.125 µg ml⁻¹ K or 0.008 µg ml⁻¹ TE). AMP ampicillin, K kanamycin, TE tetracycline